Reply To: Structure Prediction: Max Sequence Length?

Caveat: I’ve never used abrelax!

I’m not aware of any hard length restrictions on abrelax, and I find it very unlikely that they’d’ve been coded in as hard crashes instead of error messages.

I’m assuming that’s a DNA sequence (it would surely be a strange looking protein!) Are you sure that the abrelax application will fold DNA (I would guess that it doesn’t, but I have no evidence either way)?

If this is really all protein, a possibility is that with so many cysteines, the disulfide machinery is overloading and imploding.

You could always try folding a 400-mer AAAAAAA (just to check that it fails to crash).

It seems strange that it prints far less than 400 characters of sequence before crashing…