Member Site › Forums › Rosetta 3 › Rosetta 3 – General › Modeling circular permutation and domain insertion › Reply To: Modeling circular permutation and domain insertion
April 11, 2011 at 6:12 pm
#5358
I’m not aware of a good way to do this in 3.2. I’m aware of a few functional, but not stellar, ways to do this that will release in 3.3.
You could consider doing Relax with fairly tight dihedral constraints on the protein cores, and no constraints on the new linker region?