First Name
Sinisa
Middle Name
Last Name
Bjelic
Organization
Linnaeus University
Job Title
Associate Professor
Email
sinisa.bjelic@lnu.se
Research Summary
Intersted in functionalizing proteins, understanding biology, and having fun!
Research Description
The laboratory is highly interdisciplinary combining techniques across molecular modeling and experiments. The main goal of our research is to build proteins and small-molecules with therapeutic properties. Generally, we use a combination of computational molecular modeling methods (ROSETTA, MD, docking, computer scripting, etc) to theoretically predict interactions between a designed molecule and a drug target. To validate our modeling efforts, in the next step, our designs are functionally assessed by experimental techniques. Here we employ a range of basic biochemistry techniques for protein expression/purification, molecular biology, determination of molecular interactions, etc.
Research Keywords
protein–protein interface design, receptor interactions, kinases drug resistance, protein therapeutics
Working with Rosetta Since
2008