Reply To: how to get around no sequence for de novo design?

[Ora Furman]

That is right.
> Hi all,
>
> I’m playing around with designing a new protein de novo (a la Top7) for the first time, and I am wondering what sequence I should put in the fasta file for both building the fragment library and during the generation of tertiary structure by fragment assembly. Obviously, I don’t know what the sequence of the final protein should be, but both fragment selection and assembly seem to require a valid fasta file.
>
> Any ideas for a beginning designer on what the best approach is here? Thanks in advance!
>
> -Neil