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    > Hi Everyone,
    > When using the fixed backbone design program, is it possible to specify that two residues can only be changed into the same amino acid? For instance, residue 2 can be varied into any amino acid but residue 6 must be changed into whatever residue 2 is changed into.
    > Thank you!

    Hi Smlewis,

    Thanks for your response. I’ll look into the symmetry stuff. Basically, I have a beta-solenoid structure, and I would like the rungs of the solenoid to be stacked. That is, each position on each rung of the solenoid has the same amino acids.