Member Site Forums Rosetta 3 Rosetta 3 – General Bind a Ligand to RNA Reply To: Bind a Ligand to RNA


    As shipped, Rosetta3.1 is not compatible with what you want to do. It’s ultimately possible but it requires somewhere between a lot and a huge amount of fiddling with it.

    It’s not clear to me what you mean by “Create a complex” – do you mean you want to do small molecule ligand docking against an RNA rather than a protein? If you just want a mental model you can just do it manually in PyMOL…