Reply To: first try at relaxing a structure

[Anonymous]

I forgot to mention that I’m using -relax:fast. It’s good to know Rosetta isn’t a particularly viable option for this protein. I’ve been using Schrodinger Prime, but selecting a region around each residue & tweaking the endpoints until the stresses relax out isn’t fun. It takes about a week of careful tending to do it. And although there are scripts to identify stresses, they don’t correlate all that well with Molprobity criteria.

Thanks!