Reply To: Symmetric abrelax modeling

[Anonymous]

I think you’re asking, can Rosetta apply symmetry between repeats in a multidomain repeat protein.

The answer is probably not; as far as I can tell, the symmetry code enforces strict symmetry between units. The rotamer and conformation at position 10A will exactly match those at position 10B. I sent a query to the symmetry guy, but if you don’t get a further response, assume it’s a no…