Member Site Forums Rosetta 3 Rosetta 3 – Applications -score_app:linmin flag not working Reply To: -score_app:linmin flag not working


    To truly relax a protein into Rosetta’s scorefunction, use the relax application. Minimization cannot jump over energy barriers and does not perform any searching; relaxation actually searches through conformational space.

    Minimization finds the closest energy well; relaxation searches for a closeby deep energy well.