Reply To: How to dock 3 missing domains onto a multi-domain protein

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April 13, 2011 at 8:13 am #5388
Anonymous

    With respect to experimental constraints, the authors state in the paper that domain E was included in the crystal but wasn’t traced in the map. I’m not sure if I can create an starting structure of regC-D-E/cat with comparative modeling, and fit the domain E structure into the sparse map during refinement. Does this make sense?