Reply To: How to relax only one domain of a protein and keep the rest of them fixed

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April 13, 2011 at 2:16 pm #5391
Anonymous

    @smlewis

    -constrain_relax_segments flag takes a loop definition file as an input, thus I suppose it relaxes the specified loop only. I suspect this is what jtmacd was trying to do with PyRosetta. I’m currently testing the -fix_residues_to_native flag.

    @jtmacd

    I have the notion that relaxing a loop is different from relaxing a whole domain. I have tried to selectively relax my missing domain using the loop relax protocol invoked by this GUI:

    http://www.rosettacommons.org/node/2344

    but all the secondary structure of the domain disappeared.