Member Site › Forums › Rosetta 3 › Rosetta 3 – General › Modeling circular permutation and domain insertion › Reply To: Modeling circular permutation and domain insertion
April 18, 2011 at 2:29 pm
#5447
Anonymous
“loops to be internally structured ??”
Is it all loop, or does it have stretches of helix and sheet? Is it fairly rigid in the folded protein, or is it completely flexible? If it’s flexible, then you can sample where it may flex to, but there’s no point in trying to find one single structure because it won’t have only one anyway.