Reply To: computer shuts down during autobulding with rosetta

[Anonymous]

3 GB sounds like an awful lot for Rosetta to be using. Is there any tool you can use to track how much memory it has? You could set up a cron job to save “ps aux” every 5 minutes or something to see if it’s using a ton of memory before it crashes. There are probably good tools out there for this that I’m not aware of.

I don’t know if the MR protocol does much repacking. The normal way for Rosetta to gobble up TONS of memory is during protein design; generally repacking only can’t get that many rotamers. How many residues are in the problem you’re trying to solve? (I mean how many are in the Rosetta pose, not necessarily how many are in the biological protein). If that number is more than a thousand then maybe we should consider ways to pare down the rotamer memory usage.