RosettaHoles

[Anonymous]

Good Afternoon,

We were wondering if Rosetta3.3 had the ability to use scoring as described in

RosettaHoles: Rapid assessment of protein core packing for structure prediction, refinement, design, and validation by Will Sheffler and David Baker

We have searched the forum for how to utilize it but were not able to find a solution.

Any help would be greatly appreciated.

Best,
George

[Anonymous]

Packstat (the Holes application) was removed from 3.3. It is in the 3.2 version (and should work fine), try the older version. I would expect it will come out again in 3.4.

[attesor]

We use Rosetta3.4 here and we would like to here about the news of RosettaHoles, too. Could you share it, ge0rgekh0ury? Is it available in 3.4? TIA

[Anonymous]

Thanks for your response. Can you point us to an example of how to run/access packstat to be able to use RosettaHoles. We have looked in the manual are not able to understand how to use it. We have both 3.3 and 3.2 installed.
Thank you in advance.
George

[Anonymous]

Well….it was taken out of 3.3 due to the lack of documentation, so there probably isn’t any documentation in the 3.2 manual either. I’ve emailed the developer to see if he’ll help.

[Anonymous]

I passed along your email to Will, he said he’d contact you when he get a chance.

[Anonymous]

Thanks so much for your help. Have a good afternoon!

[Author]

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