the question about ddg of disulfide bond mutants

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    • #3830
      Anonymous

        I want to evaluate the ddg between WT and  disulfide bond mutants 

        1. I try to use ddg_monomer and fond it does not suport it

        2. Then I build disulfide bond mutants with moddler, and then  try to use ddg_monomer to evaluate  the ddg ( mutant  CYS  recovery to the amino acid of WT), and it does not work , too.

        3. Just as 2.  I try to use another APP, cartesian_ddg , and  disulfide bond mutants as the star model,and  ddgs seem is similar(just try three mutant)

         

        How can I evaluate the ddg between WT and  disulfide bond mutants ? Thanks

      • #16009
        Anonymous

          Could someone please answer my question?

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