Member Listing – Patrick Barth

we develop and apply computational/experimental approaches for designing proteins and cells with novel functionalities

Modeling and design of transmembrane proteins. Our long-term goal is to understand how ligand/ membrane receptor/ downstream effector systems transmit specific signals across biological membranes and to exploit this knowledge to reengineer signaling pathways. We address these objectives using a combination of computational and experimental approaches to model, design and reprogram ligand/ receptor/ effector interaction networks. Our long-term goal is to deconstruct the complex function and quantitatively describe the basic principles underlying these signaling networks.

transmembrane proteins

2005