First Name
Possu
Middle Name
Last Name
Huang
Organization
Stanford University
Job Title
Email
possu@stanford.edu
Research Summary
Protein design method development as well as developing novel cancer immunotherapy
Research Description
De novo protein design, machine learning based tool development, molecular motors, protein origami, biosensors We specializes in the development of novel protein platforms in solving biological problems. The protein design field took ten years to find a foothold in designing de novo structures (i.e. achieving full control of modeling protein backbones and sequences) and finally matured as suggested by the recent wave of publications such that we are now closer to achieving atomic-precision design of custom-made protein structures to address biomedical problems. Many challenges remain, as we are still far from achieving the complexity and functionality that nature displays. We are building a strong interdisciplinary research program to bridge this gap. Our research combines both computational and experimental aspects of protein engineering.
Research Keywords
de novo protein design,machine learning based tool development,molecular motors,protein origami,biosensors
Working with Rosetta Since
2006