First Name
Torben
Middle Name
Last Name
Schiffner
Organization
The Scripps Research Institute
Job Title
Email
torbens@scripps.edu
Research Summary
Vaccine Design
Research Description
The Schiffner lab combines computational protein design with experimental in vitro high-throughput screening methods to develop “smart” vaccine immunogens. We use technologies such as antibody/antigen interface optimization, epitope grafting, protein resurfacing, T-cell epitope engineering, glycan masking, immunogen multimerization, and protein stabilization and apply them to the rational design of next-gen immunogens against a variety of pathogens, such as Coronaviruses, Hepatitis C Virus and Human Immunodeficiency Virus.
Research Keywords
protein design
Working with Rosetta Since
2015