Member Listing – Eva-Maria Strauch

Protein design of protein-protein interactions, vaccine development, antivirals, protein stabilization, gene delivery

We are using both computational and experimental methodologies to understand, inhibit and re-purpose biological processes on the protein level. Our main focus is on how to diagnose, prevent and treat viral infections with the aim to generate new anti-virals and candidates for vaccination through protein design. For that we develop and use new cutting-edge technologies involving structural design as well as pooled oligo-synthesis and next-generation sequencing. While we are studying viral surface proteins principally to understand how we can target them or provide new immunogens, we also seek to shed light on how protein chemistry is involved in making viruses so successful. Viruses and their surface proteins hold the molecular keys for identifying specific host cells, entering them and re-programming them -- much of what we will need to fight cancer.

Protein design and engineering, protein-protein interactions, design of anti-virals and immunogens, immunoinformatics T cell epitope predictions and editing, protein chemistry and re-purposing of viral surface proteins

2008