Member Site Forums Rosetta++ Rosetta++ – General running multiple instances of rosetta Reply To: running multiple instances of rosetta


    Hi Mathew,

    You’ll want to give each instance of rosetta a different random seed.

    To do this, you’ll use two flags in your command line: -constant_seed and -jran

    The integer that follows the -jran flag should be between 1 million and 4 million.


    > I would like to run multiple instances of rosetta on a cluster in order to speed
    > up decoy generation.
    > How can I ensure that each of the decoys is original so that the conformational
    > space is searched without duplicating decoys?
    > Does rosetta have a way of creating a random seed and if so how does this alter
    > the decoy generation?
    > Thanks
    > Mathew Smith