I want to change the energy weights of rosetta2.3. It is easy to change weight in rosetta 3. I can find a weight file call “score12_full.wts“ in rosetta 3’s database. But I can’t locate the same file in rosetta 2.3. Where can I find the rosetta 2.3 energy weight file? Thank you!
This is one of many reasons why we rewrote rosetta. If my memory serves me, the score12 weights are set in score.cc, but beware that if you want to change one of the “packer weights” that they are set separately elsewhere — packer_weights.cc, it would seem. There are two weight sets in Rosetta2: one for outside the packer, and one for inside the packer. The outside weights for the packer terms, you’ll notice, are all set to 1.0 in the score12() function.