Make Fragments

[Anonymous]

We can make fragment libraries from Free Web Server : Robetta Server or Rosetta.And I want to know more details about how to create the fragment libraries.I searched in the Rosetta user Guide,just found the paper(Gront D, Kulp DW, Vernon RM, Strauss CEM and Baker D, “Generalized fragment picking in Rosetta: design, protocols and applications”, submitted to PLoS ONE)。Is there any paper about how to create the fragment libraries except that?

[Anonymous]

I think that’s the only paper that *focuses* on fragment library generation. I think this is the oldest paper describing Rosetta’s use of fragments in general: http://www.ncbi.nlm.nih.gov/pubmed/11200525 (J Biomol NMR. 2000 Dec;18(4):311-8. De novo protein structure determination using sparse NMR data. Bowers PM, Strauss CE, Baker D.). A large number of the Rosetta structure prediction papers describe fragment selection and refinements to that process.

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