what kind of focefield does Rosetta based on?

Member Site Forums Rosetta 3 Rosetta 3 – General what kind of focefield does Rosetta based on?

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    • #620

        what kind of focefield does Rosetta based on? I read all possible manuals of i Rosetta website and didn’t find any answear about this question.

        Does anybody know?

        Thank you very much.

      • #4479

          Start here:

          Methods Enzymol. 2004;383:66-93.
          Protein structure prediction using Rosetta.

          Rohl CA, Strauss CE, Misura KM, Baker D.

          PMID: 15063647 [PubMed]


          and here:

          Science. 2003 Nov 21;302(5649):1364-8.
          Design of a novel globular protein fold with atomic-level accuracy.

          Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D.

          This describes most of the scorefunction terms as of 7 years ago. Their base forms haven’t changed much although they’ve been tweaked.

          I don’t think we’ve published a review of the scorefunction since 3.0, but if I forgot one someone please correct me. There’s a major review of the overhauls in the 3.x series that’s been submitted but it doesn’t talk about the scorefunction forms, since they didn’t change much.

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